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HDAC6 antibody (N-Term)

HDAC6 Reactivity: Human WB, IF, IHC (p), ICC, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854846
  • Target See all HDAC6 Antibodies
    HDAC6 (Histone Deacetylase 6 (HDAC6))
    Binding Specificity
    • 26
    • 15
    • 11
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 121
    • 44
    • 31
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 106
    • 18
    • 1
    Rabbit
    Clonality
    • 100
    • 25
    Polyclonal
    Conjugate
    • 70
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This HDAC6 antibody is un-conjugated
    Application
    • 96
    • 37
    • 37
    • 27
    • 26
    • 26
    • 18
    • 13
    • 12
    • 10
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Rabbit Polyclonal antibody to HDAC6 (histone deacetylase 6)
    HDAC6 antibody [N1], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human HDAC6. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product HDAC6 Primary Antibody
  • Application Notes
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 3xFlag-human HDAC6-transfected 293T

    Validation: KO/KD

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.18 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    HDAC6 (Histone Deacetylase 6 (HDAC6))
    Alternative Name
    histone deacetylase 6 (HDAC6 Products)
    Background
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

    Cellular Localization: Nucleus , Cytoplasm
    Molecular Weight
    131 kDa
    Gene ID
    10013
    UniProt
    Q9UBN7
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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