FTL antibody

Catalog No. ABIN2854973

The Rabbit Polyclonal anti-FTL antibody has been validated for WB and IHC (p). It is suitable to detect FTL in samples from Human.

Quick Overview for FTL antibody (ABIN2854973)

Target: FTL (Ferritin, Light Polypeptide (FTL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FTL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FTL Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to Ferritin Light Chain (ferritin, light polypeptide)
Ferritin Light Chain antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Ferritin Light Chain. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2 , mouse liver

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.268 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Alternative Name: ferritin light chain

Background: This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.

Molecular Weight: 20 kDa

Gene ID: 2512

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis