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ACE2 antibody (N-Term)

The Rabbit Polyclonal anti-ACE2 antibody has been validated for WB, ELISA, FACS, ICC, IHC (p) and IF. It is suitable to detect ACE2 in samples from Human.
Catalog No. ABIN2855030

Quick Overview for ACE2 antibody (N-Term) (ABIN2855030)

Target

See all ACE2 Antibodies
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reactivity

  • 167
  • 59
  • 55
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 147
  • 45
  • 6
  • 1
Rabbit

Clonality

  • 126
  • 73
Polyclonal

Conjugate

  • 121
  • 17
  • 12
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ACE2 antibody is un-conjugated

Application

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  • 77
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  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Grade

KO Validated
  • Binding Specificity

    • 19
    • 16
    • 12
    • 8
    • 8
    • 8
    • 8
    • 6
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    N-Term

    Cross-Reactivity

    Green Monkey, Human, Mouse, Rat

    Characteristics

    Rabbit Polyclonal antibody to ACE2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2)
    ACE2 antibody [N1N2], N-term

    Purification

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the N-terminus region of human ACE2. The exact sequence is proprietary.

    Isotype

    IgG
  • Application Notes

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Comment

    Validation: KO/KD, Orthogonal, Overexpression

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.2 mg/mL

    Buffer

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    Alternative Name

    angiotensin I converting enzyme 2

    Background

    The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

    Cellular Localization: Processed angiotensin-converting enzyme 2: Secreted , Cell membrane

    Molecular Weight

    92 kDa

    Gene ID

    59272

    UniProt

    Q9BYF1

    Pathways

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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