PPP2CB antibody (Center)

Catalog No. ABIN2855129

The Rabbit Polyclonal anti-PPP2CB antibody has been validated for WB, IF and ICC. It is suitable to detect PPP2CB in samples from Human and Mouse.

Quick Overview for PPP2CB antibody (Center) (ABIN2855129)

Target: PPP2CB (Protein Phosphatase 2, Catalytic Subunit, beta Isozyme (PPP2CB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2CB antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-PPP2CB Antibody

Binding Specificity: Center

Cross-Reactivity: Rat (Rattus), Zebrafish (Danio rerio), Xenopus laevis, Xenopus tropicalis, Rabbit, Chicken, Rhesus Monkey, Cow (Bovine)

Cross-Reactivity (Details): Rat (100 %), Zebrafish (100 %), Xenopus laevis (100 %), Xenopus Tropicalis (100 %), Rabbit (100 %), Chicken (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to PP2A beta (protein phosphatase 2, catalytic subunit, beta isozyme)
PP2A beta antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PP2A beta. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PPP2CB

Target: PPP2CB (Protein Phosphatase 2, Catalytic Subunit, beta Isozyme (PPP2CB))

Alternative Name: PP2A beta

Background: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene.

Cellular Localization: Cytoplasm , Nucleus , Centromere , Spindle

Molecular Weight: 36 kDa

Gene ID: 5516

Pathways: Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades