RRBP1 antibody (C-Term)
Quick Overview for RRBP1 antibody (C-Term) (ABIN2855195)
Target
See all RRBP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- C-Term
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Cross-Reactivity
- Human, Mouse
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Characteristics
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Rabbit Polyclonal antibody to Ribosome binding protein 1 (ribosome binding protein 1 homolog 180 kDa (dog))
Ribosome binding protein 1 antibody [C3], C-term -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the C-terminus region of human Ribosome binding protein 1. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: NIH-3T3 , HepG2
Validation: KO/KD
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RRBP1 (Ribosome Binding Protein 1 (RRBP1))
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Alternative Name
- ribosome binding protein 1
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Background
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Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome. Alternate splicing results in multiple transcript variants.
Cellular Localization: Endoplasmic reticulum membrane, Single-pass type III membrane protein -
Molecular Weight
- 152 kDa
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Gene ID
- 6238
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UniProt
- Q9P2E9
Target
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