RRBP1 antibody (AA 1120-1200)

Catalog No. ABIN7231182

The Rabbit Polyclonal anti-RRBP1 antibody (ABIN7231182) specifically detects RRBP1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for RRBP1 antibody (AA 1120-1200) (ABIN7231182)

Target: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RRBP1 Antibody

Binding Specificity: AA 1120-1200

Purpose: Rabbit Anti-RRBP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RRBP1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RRBP1 protein at AA range: 1120-1200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RRBP1

Target: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Alternative Name: RRBP1

Background: Ribosome-binding protein 1, 180 kDa ribosome receptor homolog, RRp, ES/130-related protein, Ribosome receptor proteinRRBP1 encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of RRBP1 have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.

Molecular Weight: 155kD

Gene ID: 6238

UniProt: Q9P2E9