FAF1 antibody
Quick Overview for FAF1 antibody (ABIN2855372)
Target
See all FAF1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse
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Characteristics
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Rabbit polyclonal antibody to FAF1 (Fas (TNFRSF6) associated factor 1)
FAF1 antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human FAF1. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: H1299 , NIH-3T3
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.66 mg/mL
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Buffer
- 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))
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Alternative Name
- Fas associated factor 1
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Background
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Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain.
Cellular Localization: Nucleus -
Molecular Weight
- 74 kDa
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Gene ID
- 11124
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UniProt
- Q9UNN5
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Pathways
- Maintenance of Protein Location
Target
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