TRAF5 antibody (N-Term)
Quick Overview for TRAF5 antibody (N-Term) (ABIN2855389)
Target
See all TRAF5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Cross-Reactivity
- Human
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Characteristics
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Rabbit Polyclonal antibody to TRAF5 (TNF receptor-associated factor 5)
TRAF5 antibody [N1N3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human TRAF5. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: HeLa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.76 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- TRAF5 (TNF Receptor-Associated Factor 5 (TRAF5))
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Alternative Name
- TNF receptor associated factor 5
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Background
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The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized.
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Molecular Weight
- 64 kDa
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Gene ID
- 7188
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UniProt
- O00463
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Pathways
- NF-kappaB Signaling, Apoptosis
Target
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