ING5 antibody

Catalog No. ABIN2855407

This Rabbit Polyclonal antibody specifically detects ING5 in WB. It exhibits reactivity toward Human.

Quick Overview for ING5 antibody (ABIN2855407)

Target: ING5 (Inhibitor of Growth Family, Member 5 (ING5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ING5 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to ING5 (inhibitor of growth family, member 5)
ING5 antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ING5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ING5

Target: ING5 (Inhibitor of Growth Family, Member 5 (ING5))

Alternative Name: inhibitor of growth family member 5

Background: The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.

Molecular Weight: 28 kDa

Gene ID: 84289

UniProt: Q8WYH8

Pathways: Chromatin Binding