FASTK antibody (C-Term)

Catalog No. ABIN2855426

The Rabbit Polyclonal anti-FASTK antibody is suitable to detect FASTK in samples from Human. It has been validated for WB, ICC, IF and IHC (p).

Quick Overview for FASTK antibody (C-Term) (ABIN2855426)

Target: FASTK (Fas-Activated serine/threonine Kinase (FASTK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FASTK antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FASTK Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to FAST (Fas-activated serine/threonine kinase)
FAST antibody

Purification: Affinity purified by Protein A.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human FAST. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2 , A375 , NIH-3T3 , PC-12

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 6.56 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FASTK

Target: FASTK (Fas-Activated serine/threonine Kinase (FASTK))

Alternative Name: Fas activated serine/threonine kinase

Background: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

Molecular Weight: 61 kDa

Gene ID: 10922

UniProt: Q14296