COX15 antibody (Center)

Catalog No. ABIN2855532

This anti-COX15 antibody is a Rabbit Polyclonal antibody detecting COX15 in WB. Suitable for Human.

Quick Overview for COX15 antibody (Center) (ABIN2855532)

Target: COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COX15 Antibody

Binding Specificity: Center

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine)

Cross-Reactivity (Details): Mouse (93 %), Rat (92 %), Bovine (94 %)

Characteristics: Rabbit polyclonal antibody to COX15 (COX15 homolog, cytochrome c oxidase assembly protein (yeast))
COX15 antibody [N1C1]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human COX15. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.52 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for COX15

Target: COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))

Alternative Name: COX15

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates two transcript variants diverging in the 3' region.

Cellular Localization: Mitochondrion membrane

Molecular Weight: 46 kDa

Gene ID: 1355