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SP1 antibody (C-Term)

Name: SP1 antibody (C-Term)
Brand: antibodies-online
SKU: ABIN2855540
Price: 637.78 USD
Availability: InStock

The Rabbit Polyclonal anti-SP1 antibody has been validated for WB, IF, IHC (p) and ICC. It is suitable to detect SP1 in samples from Human.

WB Image SP1 antibody detects SP1 protein by western blot analysis. (SP1 antibody (C-Term))

IHC-P Image SP1 antibody detects SP1 protein at nucleus on human gastric carcinoma by immunohistochemical analysis. (SP1 antibody (C-Term))

IHC

IHC-P Image SP1 antibody detects SP1 protein at nucleus on human ovarian carcinoma by immunohistochemical analysis. (SP1 antibody (C-Term))

IHC

ICC/IF Image SP1 antibody detects SP1 protein at nucleus by immunofluorescent analysis. (SP1 antibody (C-Term))

WB Image Sample (30 ug of whole cell lysate) A: THP-1 5% SDS PAGE antibody diluted at 1:1000 (SP1 antibody (C-Term))

6 images

Catalog No. ABIN2855540

Quick Overview for SP1 antibody (C-Term) (ABIN2855540)

Target

See all SP1 Antibodies

SP1 (Sp1 Transcription Factor (SP1))

Reactivity

Human

Host

Rabbit

Clonality

Polyclonal

Conjugate

This SP1 antibody is un-conjugated

Application

Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Discover our top product SP1 Primary Antibody

Binding Specificity
21

12

10

7

4

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term

Cross-Reactivity

Human

Characteristics

Rabbit Polyclonal antibody to SP1 (Sp1 transcription factor)
SP1 antibody

Purification

Purified by antigen-affinity chromatography.

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human SP1. The exact sequence is proprietary.

Isotype

IgG
anti-Sp1 Transcription Factor (SP1) (pThr453) antibody
SP1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 677-707), (C-Term) antibody
SP1 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB17350 unconjugated

anti-Sp1 Transcription Factor (SP1) antibody
SP1 Reactivity: Human WB, IHC, IF, ChIP Host: Rabbit Monoclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibody
SP1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 4H6 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 522-618) antibody
SP1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4B11 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibody
SP1 Reactivity: Human WB, ELISA, IF, IHC (p) Host: Mouse Monoclonal 1A5 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 420-620) antibody
SP1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (pThr739) antibody
SP1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 89-199) antibody
SP1 Reactivity: Human, Mouse WB, ELISA, IF Host: Mouse Monoclonal 4H6 unconjugated

anti-Sp1 Transcription Factor (SP1) (AA 677-707) antibody
SP1 Reactivity: Human WB, ELISA, IHC, IF, FACS Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment

Positive Control: THP-1

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative

Thimerosal (Merthiolate)

Precaution of Use

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Target

SP1 (Sp1 Transcription Factor (SP1))

Alternative Name

Sp1 transcription factor

Background

Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

Cellular Localization: Nucleus

Molecular Weight

81 kDa

Gene ID

6667

UniProt

P08047

Pathways

Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction