IL22RA2 antibody

Catalog No. ABIN2855609

The Rabbit Polyclonal anti-IL22RA2 antibody has been validated for WB and IHC (p). It is suitable to detect IL22RA2 in samples from Human.

Quick Overview for IL22RA2 antibody (ABIN2855609)

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL22RA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IL22RA2 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to IL22 Receptor alpha 2 (interleukin 22 receptor, alpha 2)
IL22 Receptor alpha 2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human IL22 Receptor alpha 2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLaS3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for IL22RA2

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Alternative Name: interleukin 22 receptor subunit alpha 2

Background: The protein encoded by this gene is a soluble class II cytokine receptor. This protein has been shown to specifically bind to interleukin 22 (IL22), block the interaction of IL22 with its cell surface receptor, and thus inhibit IL22 activity. This protein functions as an IL22 antagonist, and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Cellular Localization: Secreted

Molecular Weight: 31 kDa

Gene ID: 116379

UniProt: Q969J5