PSMD7 antibody

Catalog No. ABIN2855679

The Rabbit Polyclonal anti-PSMD7 antibody (ABIN2855679) specifically detects PSMD7 in WB, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for PSMD7 antibody (ABIN2855679)

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-PSMD7 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to PSMD7 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 7)
PSMD7 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PSMD7. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.78 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PSMD7

Target: PSMD7 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 7 (PSMD7))

Alternative Name: proteasome 26S subunit, non-ATPase 7

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Molecular Weight: 37 kDa

Gene ID: 5713

UniProt: P51665

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway