MPI antibody

Catalog No. ABIN2855680

This Rabbit Polyclonal antibody specifically detects MPI in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for MPI antibody (ABIN2855680)

Target: MPI (Mannose Phosphate Isomerase (MPI))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-MPI Antibody

Cross-Reactivity: Human, Rat

Characteristics: Rabbit Polyclonal antibody to MPI (mannose phosphate isomerase)
MPI antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MPI. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , PC-12 , Rat2 , HeLa

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MPI

Target: MPI (Mannose Phosphate Isomerase (MPI))

Alternative Name: mannose phosphate isomerase

Background: Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.

Cellular Localization: Cytoplasm

Molecular Weight: 47 kDa

Gene ID: 4351

UniProt: P34949