ST3GAL5 antibody

Catalog No. ABIN2855684

The Rabbit Polyclonal anti-ST3GAL5 antibody has been validated for WB. It is suitable to detect ST3GAL5 in samples from Human.

Quick Overview for ST3GAL5 antibody (ABIN2855684)

Target: ST3GAL5 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST3GAL5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ST3GAL5 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5)
ST3GAL5 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human ST3GAL5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ST3GAL5

Target: ST3GAL5 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5))

Alternative Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 5

Background: Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.

Cellular Localization: Golgi apparatus membrane, Single-pass type II membrane protein

Molecular Weight: 48 kDa

Gene ID: 8869

UniProt: Q9UNP4