Seladin 1 antibody
-
- Target See all Seladin 1 (DHCR24) Antibodies
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Seladin 1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
-
Rabbit Polyclonal antibody to Seladin 1 (24-dehydrocholesterol reductase)
Seladin 1 antibody [N1C2] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human Seladin 1. The exact sequence is proprietary.
- Isotype
- IgG
-
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 227-516) antibody
DHCR24 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 57-87), (N-Term) antibodyDHCR24 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB17628 unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) antibodyDHCR24 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 218-246) antibodyDHCR24 Reactivity: Human WB Host: Rabbit Polyclonal RB17629 unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 38-87) antibodyDHCR24 Reactivity: Human, Mouse, Rat, Cow, Rabbit, Monkey WB Host: Rabbit Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 431-480) antibodyDHCR24 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Monkey, Bat WB Host: Rabbit Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
-
- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.47 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Target
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- Alternative Name
- 24-dehydrocholesterol reductase (DHCR24 Products)
- Background
-
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
Cellular Localization: Endoplasmic reticulum membrane , Golgi apparatus membrane - Molecular Weight
- 60 kDa
- Gene ID
- 1718
- UniProt
- Q15392
-
