PLA2G6 antibody

Catalog No. ABIN2855687

The Rabbit Polyclonal anti-PLA2G6 antibody has been validated for WB. It is suitable to detect PLA2G6 in samples from Human.

Quick Overview for PLA2G6 antibody (ABIN2855687)

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLA2G6 Antibody

Cross-Reactivity: Drosophila melanogaster, Human

Characteristics: Rabbit Polyclonal antibody to PLA2G6 (phospholipase A2, group VI (cytosolic, calcium-independent))
PLA2G6 antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PLA2G6. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.74 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PLA2G6

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Alternative Name: phospholipase A2 group VI

Background: The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only two of them have been determined to date.

Cellular Localization: Isoform LH-iPLA2: Membrane, Peripheral membrane protein , Isoform SH-iPLA2: Cytoplasm

Molecular Weight: 90 kDa

Gene ID: 8398

UniProt: O60733

Pathways: Positive Regulation of Peptide Hormone Secretion