SEPHS2 antibody

Catalog No. ABIN2855698

This Rabbit Polyclonal antibody specifically detects SEPHS2 in WB, IHC (p), ICC and IF. It exhibits reactivity toward Human.

Quick Overview for SEPHS2 antibody (ABIN2855698)

Target: SEPHS2 (Selenophosphate Synthetase 2 (SEPHS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEPHS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-SEPHS2 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to SEPHS2 (selenophosphate synthetase 2)
SEPHS2 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SEPHS2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.74 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SEPHS2

Target: SEPHS2 (Selenophosphate Synthetase 2 (SEPHS2))

Alternative Name: selenophosphate synthetase 2

Background: This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop. Alternatively spliced transcripts have been identified, but their biological validity has not been determined.

Molecular Weight: 47 kDa

Gene ID: 22928

UniProt: Q99611