PRSS8 antibody (Center)

Catalog No. ABIN2855739

This anti-PRSS8 antibody is a Rabbit Polyclonal antibody detecting PRSS8 in WB and IHC (p). Suitable for Human.

Quick Overview for PRSS8 antibody (Center) (ABIN2855739)

Target: PRSS8 (Protease, serine, 8 (PRSS8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PRSS8 Antibody

Binding Specificity: Center

Characteristics: Rabbit polyclonal antibody to Prostasin (protease, serine, 8)
Prostasin antibody [N1C2]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Prostasin. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , H1299 , HeLaS3 , Molt-4 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PRSS8

Target: PRSS8 (Protease, serine, 8 (PRSS8))

Alternative Name: Prostasin

Background: This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.

Cellular Localization: Prostasin: Cell membrane, Single-pass membrane protein , Prostasin light chain: Secreted , extracellular space , Prostasin heavy chain: Secreted

Molecular Weight: 36 kDa

Gene ID: 5652