ITPKC antibody

Catalog No. ABIN2855786

The Rabbit Polyclonal anti-ITPKC antibody has been validated for WB, IF and ICC. It is suitable to detect ITPKC in samples from Human.

Quick Overview for ITPKC antibody (ABIN2855786)

Target: ITPKC (Inositol-Trisphosphate 3-Kinase C (ITPKC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPKC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-ITPKC Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to IP3KC (inositol 1,4,5-trisphosphate 3-kinase C)
IP3KC antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human IP3KC. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ITPKC

Target: ITPKC (Inositol-Trisphosphate 3-Kinase C (ITPKC))

Alternative Name: inositol-trisphosphate 3-kinase C

Background: Inositol 1,4,5-trisphosphate 3-kinase (ITPK) catalyzes the phosphorylation of Ins(1,4,5)P3 to Ins(1,3,4,5)P4, both of which are modulators of calcium homeostasis. ITPK isoforms include ITPKA (MIM 147521), ITPKB (MIM 147522), and ITPKC, all of which contain a conserved catalytic unit in their C termini, but have unique N-terminal sequences and tissue distributions.[supplied by OMIM]

Cellular Localization: Nucleus , Cytoplasm

Molecular Weight: 75 kDa

Gene ID: 80271

UniProt: Q96DU7