DUSP19 antibody

Catalog No. ABIN2855788

This Rabbit Polyclonal antibody specifically detects DUSP19 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for DUSP19 antibody (ABIN2855788)

Target: DUSP19 (Dual Specificity Phosphatase 19 (DUSP19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DUSP19 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to DUSP19 (dual specificity phosphatase 19)
DUSP19 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DUSP19. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DUSP19

Target: DUSP19 (Dual Specificity Phosphatase 19 (DUSP19))

Alternative Name: dual specificity phosphatase 19

Background: Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM]

Molecular Weight: 24 kDa

Gene ID: 142679

UniProt: Q8WTR2