CPEB1 antibody (C-Term)
Quick Overview for CPEB1 antibody (C-Term) (ABIN2855898)
Target
See all CPEB1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Cross-Reactivity
- Human
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Characteristics
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Rabbit polyclonal antibody to CPEB1 (cytoplasmic polyadenylation element binding protein 1)
CPEB1 antibody [C3], C-term -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CPEB1. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: A431 , Raji
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.29 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
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Alternative Name
- cytoplasmic polyadenylation element binding protein 1
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Background
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This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Cytoplasm , P-body , Cytoplasmic granule , Cell junction , synapse , Membrane , postsynaptic cell membrane , postsynaptic density , Cell projection , dendrite -
Molecular Weight
- 63 kDa
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Gene ID
- 64506
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UniProt
- Q9BZB8
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Pathways
- Synaptic Membrane
Target
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