SKAP1 antibody

Catalog No. ABIN2856083

The Rabbit Polyclonal anti-SKAP1 antibody has been validated for WB and IHC (p). It is suitable to detect SKAP1 in samples from Human.

Quick Overview for SKAP1 antibody (ABIN2856083)

Target: SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SKAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SKAP1 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to SKAP55 (src kinase associated phosphoprotein 1)
SKAP55 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SKAP55. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SKAP1

Target: SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))

Alternative Name: src kinase associated phosphoprotein 1

Background: This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.

Cellular Localization: Cytoplasm , Nucleus , Cell membrane

Molecular Weight: 41 kDa

Gene ID: 8631

UniProt: Q86WV1