FKBP3 antibody (Center)

Catalog No. ABIN2856136

This Rabbit Polyclonal antibody specifically detects FKBP3 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for FKBP3 antibody (Center) (ABIN2856136)

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FKBP3 Antibody

Binding Specificity: Center

Cross-Reactivity: Rat (Rattus), Cow (Bovine), Xenopus tropicalis

Cross-Reactivity (Details): Rat (94 %), Bovine (97 %), Xenopus tropicalis (81 %)

Characteristics: Rabbit Polyclonal antibody to FKBP25 (FK506 binding protein 3, 25 kDa)
FKBP25 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human FKBP25. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.53 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FKBP3

Target: FKBP3 (FK506 Binding Protein 3, 25kDa (FKBP3))

Alternative Name: FKBP25

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Cellular Localization: Nucleus

Molecular Weight: 25 kDa

Gene ID: 2287