NPAS1 antibody

Catalog No. ABIN2856208

This Rabbit Polyclonal antibody specifically detects NPAS1 in WB, IHC, IF, ICC, IHC (p) and IHC (fro). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for NPAS1 antibody (ABIN2856208)

Target: NPAS1 (Neuronal PAS Domain Protein 1 (NPAS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPAS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NPAS1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to NPAS1 (neuronal PAS domain protein 1)
NPAS1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NPAS1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG , IMR32 , SK-N-AS

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-NPAS1 antibody (ABIN2856208)

Klug, Engelhardt, Cadman, Li, Smith, Ayala, Williams, Hoffman, Jin: "Differential inputs to striatal cholinergic and parvalbumin interneurons imply functional distinctions." in: eLife, Vol. 7, (2019) (PubMed).

Target Details for NPAS1

Target: NPAS1 (Neuronal PAS Domain Protein 1 (NPAS1))

Alternative Name: neuronal PAS domain protein 1

Background: The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development.

Cellular Localization: Nucleus

Molecular Weight: 63 kDa

Gene ID: 4861

UniProt: Q99742