VPS26A antibody (C-Term)

Catalog No. ABIN2856308

The Rabbit Polyclonal anti-VPS26A antibody has been validated for WB, IF, IHC (p) and ICC. It is suitable to detect VPS26A in samples from Human.

Quick Overview for VPS26A antibody (C-Term) (ABIN2856308)

Target: VPS26A (Vacuolar Protein Sorting-Associated Protein 26A (VPS26A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS26A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-VPS26A Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to VPS26 (vacuolar protein sorting 26 homolog A (S. pombe))
VPS26 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human VPS26. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.57 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for VPS26A

Target: VPS26A (Vacuolar Protein Sorting-Associated Protein 26A (VPS26A))

Alternative Name: vacuolar protein sorting 26 homolog A (S. pombe)

Background: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

Cellular Localization: Cytoplasm , Endosome membrane, Peripheral membrane protein

Molecular Weight: 38 kDa

Gene ID: 9559