USO1 antibody (C-Term)

Catalog No. ABIN2856342

This anti-USO1 antibody is a Rabbit Polyclonal antibody detecting USO1 in WB and IHC (p). Suitable for Human.

Quick Overview for USO1 antibody (C-Term) (ABIN2856342)

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-USO1 Antibody

Binding Specificity: C-Term

Characteristics: Rabbit Polyclonal antibody to VDP/p115 (USO1 homolog, vesicle docking protein (yeast))
VDP/p115 antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human VDP/p115. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:5000-1:20000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for USO1

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Alternative Name: VDP/p115

Background: The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.

Cellular Localization: Cytoplasm , cytosol , Golgi apparatus membrane, Peripheral membrane protein

Molecular Weight: 108 kDa

Gene ID: 8615