USO1 antibody (C-Term)

Catalog No. ABIN657956

There is 1 publication for this product available. The Rabbit Polyclonal anti-USO1 antibody is suitable to detect USO1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for USO1 antibody (C-Term) (ABIN657956)

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB34073

Product Details anti-USO1 Antibody

Binding Specificity: AA 932-960, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This USO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 932-960 amino acids from the C-terminal region of human USO1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: USO1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-USO1 antibody (ABIN657956)

Sui, Li, Xing, Cao, Wang, Gong, Zhang: "Lentivirus-mediated silencing of USO1 inhibits cell proliferation and migration of human colon cancer cells." in: Medical oncology (Northwood, London, England), Vol. 32, Issue 8, pp. 658, (2015) (PubMed).

Target Details for USO1

Target: USO1 (USO1 Homolog, Vesicle Docking Protein (USO1))

Alternative Name: USO1

Background: The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.

Molecular Weight: 107895

Gene ID: 8615

NCBI Accession: NP_003706

UniProt: O60763