SEC61A1 antibody (C-Term)

Catalog No. ABIN2856382

This Rabbit Polyclonal antibody specifically detects SEC61A1 in WB, IF, IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for SEC61A1 antibody (C-Term) (ABIN2856382)

Target: SEC61A1 (Sec61 alpha 1 Subunit (SEC61A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC61A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-SEC61A1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Xenopus laevis, Xenopus tropicalis, Dog (Canine), Pig (Porcine), Rhesus Monkey, Cow (Bovine)

Cross-Reactivity (Details): Mouse (100 %), Rat (100 %), Zebrafish (100 %), Xenopus laevis (93 %), Xenopus Tropicalis (100 %), Dog (100 %), Pig (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to SEC61A1 (Sec61 alpha 1 subunit (S. cerevisiae))
SEC61A1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SEC61A1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: K562 , K562 MF

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SEC61A1

Target: SEC61A1 (Sec61 alpha 1 Subunit (SEC61A1))

Alternative Name: SEC61A1

Background: The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.

Cellular Localization: Endoplasmic reticulum membrane, Multi-pass membrane protein

Molecular Weight: 52 kDa

Gene ID: 29927