SEC61A1 antibody (C-Term)

Catalog No. ABIN2790091

The Rabbit Polyclonal anti-SEC61A1 antibody (ABIN2790091) specifically detects SEC61A1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig and Goat samples.

Quick Overview for SEC61A1 antibody (C-Term) (ABIN2790091)

Target: SEC61A1 (Sec61 alpha 1 Subunit (SEC61A1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC61A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SEC61A1 Antibody

Binding Specificity: C-Term

Purpose: SEC61A1 Antibody - C-terminal region

Sequence: TWIEVSGSSA KDVAKQLKEQ QMVMRGHRET SMVHELNRYI PTAAAFGGLC

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SEC61A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SEC61A1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65273-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEC61A1

Target: SEC61A1 (Sec61 alpha 1 Subunit (SEC61A1))

Alternative Name: SEC61A1

Background:

Targeted Subunit: alpha isoform 1

Background Information: The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits.

Alternative Symbols: HNFJ4, SEC61, ADTKD5, HSEC61, SEC61A

Protein Name: Protein transport protein Sec61 subunit alpha isoform 1

Molecular Weight: 52kDa

Gene ID: 29927

NCBI Accession: NP_037468

UniProt: P61619