NOXO1 antibody (C-Term)

Catalog No. ABIN2856558

This anti-NOXO1 antibody is a Rabbit Polyclonal antibody detecting NOXO1 in WB. Suitable for Human.

Quick Overview for NOXO1 antibody (C-Term) (ABIN2856558)

Target: NOXO1 (NADPH Oxidase Organizer 1 (NOXO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOXO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NOXO1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Rat

Characteristics: Rabbit polyclonal antibody to NOXO1 (NADPH oxidase organizer 1)
NOXO1 antibody [C2C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NOXO1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HCT116

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NOXO1

Target: NOXO1 (NADPH Oxidase Organizer 1 (NOXO1))

Alternative Name: NADPH oxidase organizer 1

Background: NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). NOX organizers, such as NOXO1, target NOX activators (see NOXA1, MIM 611255) to NOX and also target NOX to different subcellular compartments (Opitz et al., 2007 [PubMed 17189823]).[supplied by OMIM]

Cellular Localization: Isoform 3: Cell membrane, Peripheral membrane protein, Cytoplasmic side

Molecular Weight: 41 kDa

Gene ID: 124056

UniProt: Q8NFA2