Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

KLRC1 antibody (N-Term)

KLRC1 Reactivity: Human WB, IF, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2856611
  • Target See all KLRC1 Antibodies
    KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
    Binding Specificity
    • 14
    • 10
    • 9
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 55
    • 9
    • 1
    • 1
    • 1
    Human
    Host
    • 52
    • 5
    • 5
    Rabbit
    Clonality
    • 54
    • 7
    • 1
    Polyclonal
    Conjugate
    • 31
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KLRC1 antibody is un-conjugated
    Application
    • 45
    • 29
    • 15
    • 10
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Rhesus Monkey, Chimpanzee
    Cross-Reactivity (Details)
    Rhesus Monkey (100 %), Chimpanzee (100 %)
    Characteristics
    Rabbit Polyclonal antibody to KLRC1 (killer cell lectin-like receptor subfamily C, member 1)
    KLRC1 antibody [N1N2], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human KLRC1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product KLRC1 Primary Antibody
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: A431 , HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.54 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
    Alternative Name
    KLRC1 (KLRC1 Products)
    Synonyms
    rNKG2A antibody, NKG2-A antibody, NKG2A antibody, KLRC1 antibody, CD159A antibody, NKG2 antibody, CD159a antibody, NKG2B antibody, killer cell lectin like receptor C1 antibody, NKG2-A/NKG2-B type II integral membrane protein-like antibody, killer cell lectin-like receptor subfamily C, member 3 antibody, killer cell lectin-like receptor subfamily C, member 1 antibody, Klrc1 antibody, KLRC1 antibody, NKG2A antibody, KLRC3 antibody
    Background
    Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.

    Cellular Localization: Membrane, Single-pass type II membrane protein
    Molecular Weight
    26 kDa
    Gene ID
    3821
You are here:
Support