KLRC4 antibody (N-Term)
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- Target See all KLRC4 Antibodies
- KLRC4 (Killer Cell Lectin-Like Receptor Subfamily C, Member 4 (KLRC4))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KLRC4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Chimpanzee
- Cross-Reactivity (Details)
- Chimpanzee (100 %)
- Characteristics
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Rabbit polyclonal antibody to KLRC4 (killer cell lectin-like receptor subfamily C, member 4)
KLRC4 antibody [N1N2], N-term - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human KLRC4. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product KLRC4 Primary Antibody
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- Application Notes
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Comment
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Positive Control: 293T
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.15 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- KLRC4 (Killer Cell Lectin-Like Receptor Subfamily C, Member 4 (KLRC4))
- Alternative Name
- KLRC4 (KLRC4 Products)
- Synonyms
- NKG2-F antibody, NKG2F antibody, killer cell lectin like receptor C4 antibody, killer cell lectin-like receptor subfamily C, member 4 antibody, KLRC4 antibody
- Background
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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3' end of the KLRC4 transcript includes the first non-coding exon found at the 5' end of the adjacent D12S2489E gene transcript.
Cellular Localization: Membrane, Single-pass type II membrane protein - Molecular Weight
- 18 kDa
- Gene ID
- 8302
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