Rab3c antibody

Catalog No. ABIN2856623

The Rabbit Polyclonal anti-Rab3c antibody has been validated for WB, IHC (p), ICC and IF. It is suitable to detect Rab3c in samples from Human. There is 1 publication available.

Quick Overview for Rab3c antibody (ABIN2856623)

Target: Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rab3c antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Grade: KO Validated

Product Details anti-Rab3c Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to RAB3C (RAB3C, member RAS oncogene family)
RAB3C antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human RAB3C Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain , H1299 , rat brain

Validation: KO/KD, Orthogonal, Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.94 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-Rab3c antibody (ABIN2856623)

Chang, Su, Chen, Chen, Chen, Hsiao: "Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis." in: Molecular cancer, Vol. 16, Issue 1, pp. 135, (2018) (PubMed).

Target Details for Rab3c

Target: Rab3c (RAB3C, Member RAS Oncogene Family (Rab3c))

Alternative Name: RAB3C, member RAS oncogene family

Background: RAB proteins, such as RAB3C, are small GTPases implicated in the regulation of vesicular trafficking between membrane compartments (Cheng et al., 2002 [PubMed 12296628]).[supplied by OMIM]

Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side

Molecular Weight: 26 kDa

Gene ID: 115827

UniProt: Q96E17