SUCLG1 antibody

Catalog No. ABIN2856658

This Rabbit Polyclonal antibody specifically detects SUCLG1 in WB, IF, IP, ICC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for SUCLG1 antibody (ABIN2856658)

Target: SUCLG1 (Succinate-CoA Ligase, alpha Subunit (SUCLG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUCLG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-SUCLG1 Antibody

Specificity: Knockdown/Knockout validation was supported by references (PMID:26990993)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to SUCLG1 (succinate-CoA ligase, alpha subunit)
SUCLG1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human SUCLG1 Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Rat brain , Mouse brain

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.48 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SUCLG1

Target: SUCLG1 (Succinate-CoA Ligase, alpha Subunit (SUCLG1))

Alternative Name: succinate-CoA ligase alpha subunit

Background: This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.

Cellular Localization: Mitochondrion

Molecular Weight: 36 kDa

Gene ID: 8802

UniProt: P53597