DUSP26 antibody (Center)
Quick Overview for DUSP26 antibody (Center) (ABIN2856665)
Target
See all DUSP26 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Center
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Cross-Reactivity
- Rat (Rattus), Rhesus Monkey, Cow (Bovine)
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Cross-Reactivity (Details)
- Rat (100 %), Rhesus Monkey (94 %), Bovine (81 %)
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Characteristics
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Rabbit Polyclonal antibody to DUSP26 (dual specificity phosphatase 26 (putative))
DUSP26 antibody [N1C1] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human DUSP26. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
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Comment
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Positive Control: NT2D1 , IMR32 , U87-MG , MCF-7 , mouse brain
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.01 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
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Alternative Name
- DUSP26
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Background
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Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
Cellular Localization: Cytoplasm , Nucleus , Golgi apparatus -
Molecular Weight
- 24 kDa
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Gene ID
- 78986
Target
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