RASAL1 antibody (C-Term)

Catalog No. ABIN2856682

This Rabbit Polyclonal antibody specifically detects RASAL1 in WB, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for RASAL1 antibody (C-Term) (ABIN2856682)

Target: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASAL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-RASAL1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Rat (Rattus)

Cross-Reactivity (Details): Rat (86 %)

Characteristics: Rabbit polyclonal antibody to RASAL1 (RAS protein activator like 1 (GAP1 like))
RASAL1 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human RASAL1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RASAL1

Target: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Alternative Name: RASAL1

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues.

Molecular Weight: 90 kDa

Gene ID: 8437