LRPPRC antibody

Catalog No. ABIN2856685

This Rabbit Polyclonal antibody specifically detects LRPPRC in WB, IF, IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for LRPPRC antibody (ABIN2856685)

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRPPRC antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Grade: KO Validated

Product Details anti-LRPPRC Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to LRP130 (leucine-rich PPR-motif containing)
LRP130 antibody [N3C2], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human LRP130. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299 , HeLa , mouse brain , 293T

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.36 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Alternative Name: leucine rich pentatricopeptide repeat containing

Background: This gene encodes a protein that is leucine-rich and is thought to play a role in regulating the interaction of the cytoskeleton with a variety of cellular processes. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. Transcripts ranging in size from 4.8 to 7.0 kb which result from alternative polyadenylation have been reported for this gene.

Cellular Localization: Mitochondrion , Nucleus , nucleoplasm , Nucleus inner membrane , Nucleus outer membrane

Molecular Weight: 158 kDa

Gene ID: 10128

UniProt: P42704