PTS antibody
Quick Overview for PTS antibody (ABIN2856764)
Target
See all PTS AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Cross-Reactivity
- Human, Mouse
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Characteristics
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Rabbit Polyclonal antibody to PTS (6-pyruvoyltetrahydropterin synthase)
PTS antibody [N1C3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Full length human PTS Recombinant protein.
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Isotype
- IgG
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Application Notes
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: Mouse stomach , H1299 , HeLa , PTS-transfected 293T
Validation: KO/KD, Overexpression
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- PTS (6-Pyruvoyltetrahydropterin Synthase (PTS))
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Alternative Name
- 6-pyruvoyltetrahydropterin synthase
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Background
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The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.
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Molecular Weight
- 16 kDa
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Gene ID
- 5805
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UniProt
- Q03393
Target
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