RRAS2 antibody (Center)

Catalog No. ABIN2856766

This Rabbit Polyclonal antibody specifically detects RRAS2 in WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for RRAS2 antibody (Center) (ABIN2856766)

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRAS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RRAS2 Antibody

Binding Specificity: Center

Cross-Reactivity: Rat (Rattus), Rhesus Monkey, Cow (Bovine)

Cross-Reactivity (Details): Rat (100 %), Rhesus Monkey (100 %), Bovine (100 %)

Characteristics: Rabbit Polyclonal antibody to TC21 (related RAS viral (r-ras) oncogene homolog 2)
TC21 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TC21. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.69 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RRAS2

Target: RRAS2 (Related RAS Viral (R-Ras) Oncogene Homolog 2 (RRAS2))

Alternative Name: TC21

Background: This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants.

Cellular Localization: Cell membrane, Lipid-anchor, Cytoplasmic side (By similarity)

Molecular Weight: 23 kDa

Gene ID: 22800