CHP antibody (Internal Region)
Quick Overview for CHP antibody (Internal Region) (ABIN2856827)
Target
See all CHP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Cross-Reactivity
- Rat (Rattus)
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Cross-Reactivity (Details)
- Rat (100 %)
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Characteristics
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Rabbit Polyclonal antibody to Calcium binding protein P22
Calcium binding protein P22 antibody [N2C2], Internal -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Calcium binding protein P22. The exact sequence is proprietary.
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Isotype
- IgG
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Application Notes
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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Comment
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Positive Control: HepG2
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CHP (Calcium Binding Protein P22 (CHP))
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Alternative Name
- Calcium Binding Protein P22
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Background
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This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity.
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Molecular Weight
- 22 kDa
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Gene ID
- 11261
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Pathways
- Proton Transport, Regulation of Carbohydrate Metabolic Process, VEGF Signaling
Target
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