RecQ Protein-Like (DNA Helicase Q1-Like) (RECQL) (N-Term) antibody

Catalog No. ABIN2857056

This anti- antibody is a Rabbit Polyclonal antibody detecting in WB, IF, IHC (p), IP and ICC. Suitable for Human.

Quick Overview for RecQ Protein-Like (DNA Helicase Q1-Like) (RECQL) (N-Term) antibody (ABIN2857056)

Target: RecQ Protein-Like (DNA Helicase Q1-Like) (RECQL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details

Binding Specificity: N-Term

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Bovine (86 %)

Characteristics: Rabbit polyclonal antibody to RecQ1 (RecQ protein-like (DNA helicase Q1-like))
RecQ1 antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human RecQ1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*

Comment:

Positive Control: A431 , HeLa , A375

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details

Target: RecQ Protein-Like (DNA Helicase Q1-Like) (RECQL)

Alternative Name: RecQ1

Background: The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.

Cellular Localization: Nucleus

Molecular Weight: 73 kDa

Gene ID: 5965