HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) antibody

Catalog No. ABIN2857073

The Rabbit Polyclonal anti- antibody has been validated for WB, IHC (p), ICC, IF and IP. It is suitable to detect in samples from Human.

Quick Overview for HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) antibody (ABIN2857073)

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to TIP30 (HIV-1 Tat interactive protein 2, 30 kDa)
TIP30 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human TIP30 Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431 , HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details

Target: HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)

Alternative Name: HIV-1 Tat interactive protein 2

Background: Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.

Cellular Localization: Cytoplasm , Nucleus envelope

Molecular Weight: 27 kDa

Gene ID: 10553

UniProt: Q9BUP3