PDGFRB antibody (AA 1013-1025)

Catalog No. ABIN285907

This Rabbit Polyclonal antibody specifically detects PDGFRB in WB, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for PDGFRB antibody (AA 1013-1025) (ABIN285907)

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRB antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-PDGFRB Antibody

Binding Specificity: AA 1013-1025

Cross-Reactivity: Mouse (Murine)

Purification: Protein G affinity chromatography

Immunogen: PDGF receptor beta antibody was raised in rabbit using a synthetic peptide (QPNEGDNDYIIPLA) corresponding to amino acids 1013-1025 of human PDGF receptor beta as the immunogen.

Isotype: IgG

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Frozen

Concentration: Lot specific

Buffer: Frozen in 0.1 M tris-glycine buffer, pH 7.4, with 0.11 NaCl, and 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Alternative Name: PDGF Receptor beta

Background: Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.

Molecular Weight: 190 kDa (predicted detection band MW)

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling