CEA
Reactivity: Human
WB, IHC, IP, ICC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Concentration
Lot specific
Buffer
50 mM PBS, pH 7.2, with BSA, and thimerosal.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
DO NOT FREEZE. Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase. Dilute only prior to immediate use.
Storage
4 °C
Target
CEA
(Carcinoembryonic Antigen Gene Family (CEA))
Alternative Name
CEA
Background
Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.