CXCL12 antibody (Biotin)

Catalog No. ABIN288472

This Goat Polyclonal antibody specifically detects CXCL12 in WB, ELISA and Inhibition. It exhibits reactivity toward Mouse.

Quick Overview for CXCL12 antibody (Biotin) (ABIN288472)

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This CXCL12 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Product Details anti-CXCL12 Antibody (Biotin)

Immunogen: SDF1 alpha antibody (biotin) was raised in goat using highly pure recombinant murine SDF-1 alpha as the immunogen.

Application Details

Application Notes: ELISA: 0.5-2 µg/mL, Inhibition: 2.5-3.5 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for CXCL12

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Alternative Name: SDF1 alpha

Background: SDF-1 alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.

Molecular Weight: 7.9 kDa (predicted detection band MW)

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling