HLA-ABC antibody (PE)

Catalog No. ABIN294421

This Mouse Monoclonal antibody specifically detects HLA-ABC in FACS, IP and ELISA. It exhibits reactivity toward Human, Cow and Primate.

Quick Overview for HLA-ABC antibody (PE) (ABIN294421)

Target: HLA-ABC

Reactivity: Human, Cow, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLA-ABC antibody is conjugated to PE

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA

Clone: MEM-123

Product Details anti-HLA-ABC Antibody (PE)

Specificity: Reacts with all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. The antibody MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks the antibody MEM-G/9

Purification: Protein A purified

Immunogen: COS-7 African green monkey kidney cells.

Isotype: IgG3

Application Details

Application Notes: Approved: ELISA, Flo (4 μg/mL), IP

Usage: The antibody MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks the antibody MEM-G/9. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, 0.2 % high-grade protease free BSA as a stabilizing agent.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light. Store undiluted.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light. Store undiluted.

Target Details for HLA-ABC

Target: HLA-ABC

Alternative Name: HLA-A/B/C

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints