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Abeta 1-40 antibody

This anti-Abeta 1-40 antibody is a Mouse Monoclonal antibody detecting Abeta 1-40 in IHC, WB, IP, ELISA and IF. Suitable for Mouse and Human.
Catalog No. ABIN2961827

Quick Overview for Abeta 1-40 antibody (ABIN2961827)

Target

See all Abeta 1-40 Antibodies
Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Reactivity

  • 17
  • 16
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Mouse, Human

Host

  • 17
  • 1
Mouse

Clonality

  • 17
  • 1
Monoclonal

Conjugate

  • 6
  • 1
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  • 1
  • 1
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  • 1
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  • 1
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  • 1
This Abeta 1-40 antibody is un-conjugated

Application

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Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

Clone

Ab40-1
  • Specificity

    Reacts with human and mouse Aβx-40

    Purification

    Purified

    Immunogen

    Synthetic peptide corresponding to Abeta35-40.

    Isotype

    IgG1
  • Application Notes

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    1 - 10 μg/mL for any application

    Restrictions

    For Research Use only
  • Buffer

    PBS pH 7.4

    Handling Advice

    Dilute in PBS or medium which is identical to that used in the assay system.

    Storage

    -20 °C

    Storage Comment

    Stable for at least one year at -20°C

    Expiry Date

    12 months
  • Target

    Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

    Alternative Name

    Amyloid beta 1-40

    Background

    Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Aβ (Aβ42) and amino-terminally truncated forms of Aβ (Aβx-42) are the predominant species of Aβ typically found in diffuse and senile plaques within the AD brain. There is a strong correlation between Aβ40 positivity and mature plaques. In the AD cortex, diffuse plaques, representing the earliest stage of Aβ deposition, are positive for Aβ42, but negative for Aβ40.

    Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Beta-amyloid protein 40 Beta-APP40 Gene name: APP, A4, AD1

    Gene ID

    351

    UniProt

    P05067
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