Abeta 1-40 antibody
Quick Overview for Abeta 1-40 antibody (ABIN2961827)
Target
See all Abeta 1-40 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with human and mouse Aβx-40
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Purification
- Purified
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Immunogen
- Synthetic peptide corresponding to Abeta35-40.
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Isotype
- IgG1
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Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL for any application -
Restrictions
- For Research Use only
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Buffer
- PBS pH 7.4
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Handling Advice
- Dilute in PBS or medium which is identical to that used in the assay system.
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Storage
- -20 °C
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Storage Comment
- Stable for at least one year at -20°C
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Expiry Date
- 12 months
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- Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))
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Alternative Name
- Amyloid beta 1-40
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Background
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Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Aβ (Aβ42) and amino-terminally truncated forms of Aβ (Aβx-42) are the predominant species of Aβ typically found in diffuse and senile plaques within the AD brain. There is a strong correlation between Aβ40 positivity and mature plaques. In the AD cortex, diffuse plaques, representing the earliest stage of Aβ deposition, are positive for Aβ42, but negative for Aβ40.
Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Beta-amyloid protein 40 Beta-APP40 Gene name: APP, A4, AD1 -
Gene ID
- 351
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UniProt
- P05067
Target
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