Abeta 1-42 antibody

Catalog No. ABIN2961828

This Mouse Monoclonal antibody specifically detects Abeta 1-42 in WB, IHC, IP, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for Abeta 1-42 antibody (ABIN2961828)

Target: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Abeta 1-42 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

Clone: Ab42-2

Product Details anti-Abeta 1-42 Antibody

Specificity: Reacts with human and mouse Aβx-42

Purification: Purified

Immunogen: Synthetic peptide corresponding to Abeta35-42.

Isotype: IgG1

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL

Restrictions: For Research Use only

Handling

Buffer: PBS pH 7.4

Handling Advice: Dilute in PBS or medium which is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Stable for at least one year at -20°C

Expiry Date: 12 months

Target Details for Abeta 1-42

Target: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Alternative Name: Amyloid beta 1-42

Background: Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Aβ (Aβ42) and amino-terminally truncated forms of Aβ (Aβx-42) are the predominant species of Aβ typically found in diffuse and senile plaques within the AD brain. The relative levels of Aβ42 appear to be the key regulators of Aβ aggregation into amyloid, thus Aβ42 has been implicated as the initiating molecule in the pathogenesis of AD.

Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Beta-amyloid protein 42 Beta-APP42 Gene name: APP, A4, AD1

Gene ID: 351

UniProt: P05067